Minimally Invasive Drainage Implant: 3-Year Follow-up

Sunday, April 27, 2014: 1:57 PM
Room 155 (Boston Convention and Exhibition Center)
Juan F. Batlle, MD, Centro Laser, Santo Domingo, Dominican Republic
Paul F. Palmberg, MD, PhD, University of Miami Miller School of Medicine, Miami, FL, USA

Narrative Responses:

Purpose
To report the experience of the minimally invasive drainage implant (InnFocus-MIDI Arrow) in patients with glaucoma. The purpose of this study is to evaluate the IOP lowering effects of the microshunt used either alone or in combination with phacoemulsification for a period of three years.

Methods
Twenty-one eyes included; 8 eyes underwent combined glaucoma and phacoemulsification surgery and 13 eyes had glaucoma procedures alone.  All eyes received an intraoperative wide application under the subconjunctival flap of 0.4 mg/mL of Mitomycin C for three minutes.  The flexible tube made of the biocompatible material SIBS was implanted through a 3 mm long needle track made with a 27 g needle.

Results
The average medicated baseline IOP was 23.9 ± 5.4 mmHg (n=21).  The average IOP dropped 56% to 10.6 ± 2.8 mmHg (n=21) and 52% to 11.4 ± 3.0 mmHg (n=17) at 1 and 2 years, respectively.  The success rate, measured by dropping IOP by ≥20% without surgical intervention, was 100% (21/21) and 94% (16/17) at 1 and 2-years, respectively.  There were two cases of transient hypotony and two choroidal effusions which cleared spontaneously.  There were no long-term sight-threatening adverse events.

Conclusion
The InnFocus MicroShunt effectively lowered IOP by 56% and 52% with 90% and 88% of patients achieving IOP of ≤ 14 mmHg at one and two years, respectively without serious long-term adverse events. The simplicity of use and ease of follow-up will provide a simple and effective replacement for trabeculectomy.