Light Transmittance of Cadaver-Eye Explanted Single-Piece Hydrophobic Acrylic IOLs With Surface Light Scattering
Narrative Responses:
Purpose
To investigate the potential effect of surface light scattering on light transmittance of single-piece hydrophobic acrylic intraocular lenses (IOLs) with or without blue-light filter.
Methods
IOLs were obtained from human cadavers (49 IOLs total; 36 with blue-light filter), and from finished-goods inventory (controls). The IOLs were explanted from cadaver eyes and power/model matched to unused controls. After removing surface proteins, IOLs were allowed to hydrate for 24 hours at room temperature. Surface light scattering was measured with a Scheimpflug camera (EAS-1000 Anterior Segment Analysis System, Nidek, Ltd.). Light transmittance was measured with a Perkin Elmer Lambda 35 UV/Vis spectrophotometer (single-beam configuration; RSA-PE-20 integrating sphere).
Results
Hydrated scatter values ranged from 4.8 to 202.5 computer-compatible tape units (CCT) for explanted IOLs with blue-light filter and 1.5 to 11.8 CCT for controls; values ranged from 6.0 to 137.5 CCT for explanted IOLs without blue-light filter and 3.5 to 9.6 CCT for controls. In both groups, there was a tendency for increasing scatter values with increasing postoperative time. No differences in light transmittance were observed between explanted IOLs and controls for both groups (blue-light filter IOLs: P = .407, paired t test; non-blue-light filter IOLs: P = .487, paired t test).
Conclusion
Although surface light scattering of explanted IOLs was significantly higher than that of controls and appeared to increase with time, no effect was observed on light transmittance of single-piece hydrophobic acrylic IOLs with or without blue-light filter.