Light Transmittance of Cadaver-Eye Explanted Single-Piece Hydrophobic Acrylic IOLs With Surface Light Scattering

Friday, April 25, 2014
KIOSKS (Boston Convention and Exhibition Center)
Liliana Werner, MD, PhD, John A. Moran Eye Center, Salt Lake City, UT, USA
Caleb K. Morris, BA, University of Utah Moran Eye Center, Durham, NC, USA
Erica T. Liu, MD, University of Utah Moran Eye Center, Salt Lake City, UT, USA
Shannon L. Stallings, MD, Howard University Hospital, Washington, DC, USA
Anne M. Floyd, MD, MS, University of Utah / Moran Eye Center, Salt Lake City, Utah, USA

Narrative Responses:

Purpose
To investigate the potential effect of surface light scattering on light transmittance of single-piece hydrophobic acrylic intraocular lenses (IOLs) with or without blue-light filter.

Methods
IOLs were obtained from human cadavers (49 IOLs total; 36 with blue-light filter), and from finished-goods inventory (controls). The IOLs were explanted from cadaver eyes and power/model matched to unused controls. After removing surface proteins, IOLs were allowed to hydrate for 24 hours at room temperature. Surface light scattering was measured with a Scheimpflug camera (EAS-1000 Anterior Segment Analysis System, Nidek, Ltd.). Light transmittance was measured with a Perkin Elmer Lambda 35 UV/Vis spectrophotometer (single-beam configuration; RSA-PE-20 integrating sphere).

Results
Hydrated scatter values ranged from 4.8 to 202.5 computer-compatible tape units (CCT) for explanted IOLs with blue-light filter and 1.5 to 11.8 CCT for controls; values ranged from 6.0 to 137.5 CCT for explanted IOLs without blue-light filter and 3.5 to 9.6 CCT for controls. In both groups, there was a tendency for increasing scatter values with increasing postoperative time. No differences in light transmittance were observed between explanted IOLs and controls for both groups (blue-light filter IOLs: P = .407, paired t test; non-blue-light filter IOLs: P = .487, paired t test).

Conclusion
Although surface light scattering of explanted IOLs was significantly higher than that of controls and appeared to increase with time, no effect was observed on light transmittance of single-piece hydrophobic acrylic IOLs with or without blue-light filter.