<span>Light-Scattering and Light-Transmittance Findings in a Series of Calcified Single-Piece Hydrophilic Acrylic IOLs of the Same Design</span>

Barra, Daniel

Light-Scattering and Light-Transmittance Findings in a Series of Calcified Single-Piece Hydrophilic Acrylic IOLs of the Same Design

Monday, April 28, 2014: 3:11 PM

Room 151A (Boston Convention and Exhibition Center)

Daniel R. Barra, MD, Visao Institutos, Brasilia, Brazil

Liliana Werner, MD, PhD, John A. Moran Eye Center, Salt Lake City, UT, USA

Bruna V. Ventura, MD, Altino Ventura Foundation, Recife, Brazil

João Luiz P. Costa, MD, Visão Institutos, BRASILIA, Brazil

Tiago S. Ribeiro, MD, Visão intitutos oftalmologicos, Brasília, Brazil

Caleb K. Morris, BA, University of Utah Moran Eye Center, Durham, NC, USA

Fabio Dornelles, MD, Visum Oftalmologia, Porto Alegre - RS, Brazil

Narrative Responses:

Purpose
To evaluate light scattering and light transmittance of Ioflex hydrophilic acrylic intraocular lenses (IOLs) explanted due to clinically significant opacification secondary to calcification.

Methods
Seven (7) explanted lenses and 8 control Ioflex lenses were studied. Gross and light microscopy were performed for all lenses. Light scattering was measured with a Nidek EAS 1000 Scheimpflug camera. Light transmittance was assessed using a Perkin Elmer Lambda 35 UV/Vis spectrophotometer (single beam configuration with a Lab Sphere RSA PE 20 integrating sphere). Analyses were performed at room temperature in the hydrated state, and compared to controls.

Results
Light scattering was 219.71 ± 2.62 CCT for explanted IOLs, and 4.75 ± 2.50 CCT for controls IOLs. The average light transmittance in the visible light spectrum was 75.94% to 87.25% for explanted IOLs, and 97.54% to 98.97% for control IOLs. The most striking finding was variable degrees of light transmittance in the region between 290 and 350 nm (ultraviolet A and B radiation) in the explanted and control lenses with expiration dates in 2009/2010, while 0% transmittance in this region was observed in all control lenses with expiration dates in 2011/2012.

Conclusion
Light scattering was extremely high, and transmittance was significantly reduced in calcified lenses. Differences in transmittance observed in the 290-350 nm region between lenses with different expiration dates were related to use of different hydrophilic acrylic raw material suppliers for Ioflex manufacture, further highlighting the complexity of IOL calcification investigations.