Femtosecond Laser Zig-Zag DALK for Treatment of Corneal Stromal Pathology

Farid, Marjan

Femtosecond Laser Zig-Zag DALK for Treatment of Corneal Stromal Pathology

Sunday, April 27, 2014: 8:57 AM

Room 151B (Boston Convention and Exhibition Center)

Marjan Farid, MD, UC-Irvine, Irvine, CA, USA

Sumit (Sam) Garg, MD, Gavin Herbert Eye Institute, Irvine, California, USA

Roger F. Steinert, MD, UC Irvine, Irvine, California, USA

Matthew Wade, MD, UC Irvine, Irvine, California, USA

Kristin Hirabayashi, University of California, Irvine, CA, USA

Narrative Responses:

Purpose

To determine outcomes and efficacy of femtosecond laser zig-zag deep anterior lamellar keratoplasty (DALK).

Methods
A retrospective analysis of 30 eyes of 29 patients that were treated by femtosecond zig-zag DALK was performed. Outcomes including corrected distance visual acuity (CDVA), topographic and manifest astigmatism, and complications were reviewed.

Results
Full big bubble baring of Descemet’s membrane (DM) was achieved in 28 eyes. In those eyes that had full baring of DM, the average CDVA at post-operative month 6 was LogMar 0.26 (20/36 Snellen acuity). Mean topographic astigmatism was 3.7 D (range 1.1-6.6 D) and mean manifest astigmatism was 2.6 D (range 0-5.5 D) in all eyes. These outcomes were maintained or improved throughout the follow up period out to 3.5 years. One case had a repeat big-bubble DALK due to stromal rejection.

Conclusion
Femtosecond laser zig-zag DALK results in early and stable excellent visual recovery and post-operative astigmatism. For eyes with healthy endothelium, this technique offers avoidance of endothelial rejection risk without evidence of compromise in the optical performance.