Relationship Between Posterior Capsule Wrinkle and Intraocular Lens

Friday, April 25, 2014
KIOSKS (Boston Convention and Exhibition Center)
Mayumi Nagata, MD, PhD, Dokkyo Medical University, Mibu, Japan
Hiroyuki Matsushima, MD, PhD, Dokkyo Medical University, Mibu, Japan

Narrative Responses:

Purpose
The posterior capsular wrinkle can sometimes be observed after intraocular lens (IOL) implantation. However, mechanisms of the wrinkles are not well known. In this study, we analyzed the relationship between posterior capsular wrinkle and IOL.

Methods
Subjects comprised 66 eyes that underwent phacoemulsification. Single piece IOL (NY-60, HOYA) 36 eyes or three piece IOL (PY-60AD, HOYA) 30 eyes were randomly implanted. The mean age of patients is 72.3±7.4.

Images were taken using an EAS-1000 (NIDEK) after 1 week, 1, 3, 6 months and 1 year postoperatively. And the patients were divided into a wrinkle group (the wrinkle was recognized in posterior capsule) and a no-wrinkle group. In the wrinkle group, the relationship between the position of wrinkle and the position of optic-haptic junctions were analyzed. And also the axial length were compared in two groups.

Results
The wrinkle were observed in 1 eye of NY-60 group (2.8%), 11 eyes of PY-60AD group (36.7%). In NY-60 group, the wrinkle was appeared at 1 month postoperatively, and in PY-60AD group, wrinkle were appeared immediately after surgery and were not decreased for 1 year postoperatively. In the wrinkle group, the direction of wrinkle were placed at an angle of 55.4±3.6 degree from optic-haptic junctions regularly. The axial length were 23.47±1.03 mm in the wrinkle group and 24.50±1.24 mm in the no-wrinkle group. There were statistically significance in two groups (P = 0.02).

Conclusion
The ratio of wrinkle incidence differed depending on the shape of IOLs. The wrinkle placed to direction of vertex in haptics. And the wrinkle often occurs in short axial length eyes that have small lens capsules.