Femto Laser-Assisted LASIK Versus Laser-Assisted Subepithelial Keratectomy for Correction of High Myopia and Astigmatism
Narrative Responses:
Purpose
To compare the visual and refractive outcomes and higher-order aberration changes of FA-LASIK versus LASEK in the treatment of high myopia and astigmatism.
Methods
A prospective comparative case series study comprised 36 eyes of patients with manifest refraction spherical component greater than -6.00 diopters (D) and cylinder components lower than -3.00 D were assigned to 2 groups: 26 eyes were treated with FA-LASIK and 12 eyes with LASEK. Uncorrected visual acuity (UCVA), distant corrected visual acuity (DCVA), higher-order aberration (HOAs) changes and complications were evaluated at 1 week, 2, and 6 months postoperatively.
Results
Preoperatively the mean refractive spherical equivalent (MRSE) was -6.99 ±1.58SD in FA-LASIK group and -6.58 ±0.75D in LASEK group, at 1 week and 6 months it was -0.19 ±0.38 and -0.26±0.33, -0.25±0.67 and -0.16±0.36 respectively. There were no any statistically significant differences in term of UCVA P=0.35, DCVA P=1.0, Defocus p=0.16, Cylinder p=0.99D, HOA changes p=0.22, safety index p=0.35, efficacy index p=0.13, and gained 1 line or more of DCVA in all postoperative visits between groups. Spherical aberration was increased significantly in LASEK group p=0.03.
Conclusion
Both customized FA-LASIK and LASEK were safe and effectively treated eyes with high myopia and astigmatism.