Repeat Penetrating Keratoplasty in Patients With Herpetic Stromal Keratitis

Friday, April 25, 2014
KIOSKS (Boston Convention and Exhibition Center)
Osman S. Arslan, MD, Istanbul University, Cerrahpasa Faculty of Medicine, Ophtalmology Department, Istanbul, Turkey
Ceyhun Arici, MD, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey
Mehmet S. Mangan, MD, Istanbul University Cerrahpasa School of Medicine, Istanbul, Turkey
Eray Atalay, Istanbul University, Istanbul, Turkey
Mustafa I. Toker, MD, Cumhuriyet Univ Medical School, Sivas, Turkey

Narrative Responses:

Purpose
To report the clinical outcome of corneal regrafting in adult patients with stromal keratitis of herpetic after a failed first graft.

Methods
In this retrospective, observational case series, repeat penetrating keratoplasty (PK)was performed in 32 eyes of 32 adult patients having herpetic stromal keratitis and graft failure, between january 1, 2005 and january 1, 2012. Main outcome measures are graft survival, best corrected visual acuity (BCVA) in preoperatively and postoperative six months.

Results
At the time of surgery, the mean patient age was 36.08±7.80 years. The mean follow-up period was 31.42±14.10 months, ranging from 10 to 67 months. 25 of 32 eyes (78.1%) were clear graft at six months after repeat PK. No intraoperative complications were observed. The mean logMar BSCVA of patients were 1.79±0.76 in preoperative period. At 6 months after surgery, the mean logMar BSCVA of 25 patients having clear graft was 0.48±0.33.

Conclusion
Repeat PK for the visual rehabilitation of graft failure associated with herpetic stromal keratitis is a safe and effective surgical method in adult patients.