Nuances of Intracameral Use of Triamcinolone After Uncomplicated Cataract Surgery

Sunday, April 27, 2014: 3:23 PM
Room 152 (Boston Convention and Exhibition Center)
Debashis Dutta, MS, DISHA, Kolkata, India

Narrative Responses:

Purpose
To find out how safe is it to use intracameral triamcinolone as a routine postoperative medication. Can we do away with topical postoperative drops altogether? Does it affect the endothelial count? What is the incidence of increase of intraocular pressure? Are the patients satisfied and comfortable?

Methods
100 eyes of 100 patients undergoing phacoemulsification were randomized into two groups prospectively.Patients with systemic or ocular disease were excluded.At the end of surgery, eyes in group A were injected with 1 mg/0.1 ml TA into the anterior chamber and no topical drop was used. In group B postoperatively topical prednisolone 1% drops was applied 6 times per day for 7 days, then 4 times per day for 15 days and 2 times per day for 15 days to control inflammation.Preoperative and serial postoperative specular count,IOP,Anterior chamber cells and flare was noted on 1st,7th and 30th day.

Results
Both treatments were equally effective in controlling postoperative inflammation following phacoemulsification. No statistically significant differences between groups were observed for the efficacy, safety and tolerance variables, and no serious adverse events were observed.There were no reports of increase of IOP in either group.In TA group 98% patients group did not require any topical  medications and specular count did not reveal any endothelial toxicity.

Conclusion
Intracameral TA of 1 mg can effectively be used to control postoperative inflammation after uncomplicated routine cataract surgery with phacoemulsification. This decreases the need of topical prednisolone(98%) and patients were very happy as they had  to apply minimum drops after operation.