Evaluation of Trabecular Micro-Bypass Stent With Phacoemulsification in Patients With Open-Angle Glaucoma and Cataract

Sunday, April 27, 2014: 1:01 PM
Room 155 (Boston Convention and Exhibition Center)
John P. Berdahl, MD, Vance Thompson Vision, Sioux Falls, SD, USA
Justin A. Schweitzer, OD, Vance Thompson Vision, Sioux Falls, SD, USA
Tanner J. Ferguson, Morningside College, Dakota Dunes, SD, USA

Narrative Responses:

Purpose
Purpose: To evaluate the safety and efficacy of the iStent Trabecular Micro-Bypass stent in combination with cataract surgery in patients with open-angle glaucoma.

Methods
Methods: Retrospective, consecutive case series from cases between October 2012 and August 2013. The series was comprised of 133 eyes with open-angle glaucoma. Data were collected pre-operatively, and follow-up data were collected at 1 day, 1 week, 1 month, 3 months and 6 months. Data included intraocular pressure (IOP), number of glaucoma medications, visual acuity (VA), the incidence of post-operative IOP pressure increases (≥15mmHg), and need for additional surgery.

Results
Results: The mean pre-operative IOP was 19.2 ± 6.9 mmHg. At 6 months postoperative, mean IOP was 14.7± 4.1 mmHg (p<0.05).  The mean number of glaucoma medications was 1.40 ± 1.03 pre-operatively and 0.98 ± 1.28 (p<0.05) at 6 months postoperativeThe mean best spectacle corrected acuity was 0.3±0.1 pre-operatively and p, 0.2±0.1 at 6 months postoperative. At week 1, 2 patients experienced IOP increase of 15mmHg above their baseline IOP that responded to topical therapy. No patients required additional surgery.

Conclusion
Conclusions:  The insertion of the iStent Trabecular Micro-Bypass stent in combination with cataract surgery is effective in significantly lowering IOP in open-angle glaucoma patients.  Medication use was significantly reduced postoperatively.  The safety profile appears favorable with no need for additional surgery.