Evaluation of Trabecular Micro-Bypass Stent With Phacoemulsification in Patients With Open-Angle Glaucoma and Cataract
Narrative Responses:
Purpose
Purpose: To evaluate the safety and efficacy of the iStent Trabecular Micro-Bypass stent in combination with cataract surgery in patients with open-angle glaucoma.
Methods
Methods: Retrospective, consecutive case series from cases between October 2012 and August 2013. The series was comprised of 133 eyes with open-angle glaucoma. Data were collected pre-operatively, and follow-up data were collected at 1 day, 1 week, 1 month, 3 months and 6 months. Data included intraocular pressure (IOP), number of glaucoma medications, visual acuity (VA), the incidence of post-operative IOP pressure increases (≥15mmHg), and need for additional surgery.
Results
Results: The mean pre-operative IOP was 19.2 ± 6.9 mmHg. At 6 months postoperative, mean IOP was 14.7± 4.1 mmHg (p<0.05). The mean number of glaucoma medications was 1.40 ± 1.03 pre-operatively and 0.98 ± 1.28 (p<0.05) at 6 months postoperativeThe mean best spectacle corrected acuity was 0.3±0.1 pre-operatively and p, 0.2±0.1 at 6 months postoperative. At week 1, 2 patients experienced IOP increase of 15mmHg above their baseline IOP that responded to topical therapy. No patients required additional surgery.
Conclusion
Conclusions: The insertion of the iStent Trabecular Micro-Bypass stent in combination with cataract surgery is effective in significantly lowering IOP in open-angle glaucoma patients. Medication use was significantly reduced postoperatively. The safety profile appears favorable with no need for additional surgery.