Optical Coherence Tomography Features in Unilateral and Bilateral Pseudoexfoliation Syndrome Versus Normal Eye
Narrative Responses:
Purpose
To evaluate choroidal thickness using optical coherence tomography (OCT) in affected unilateal and bilateral pseudoexfoliation (PEX) syndrome and to compare them with healthy controls.
Methods
Twenty seven patients with unilateral PEX syndrome which affected eye (right eye of 15 patient, left eye of 12 patient) included group 1, those who unilateral PEX syndrome unaffected eye included group 2, twenty seven with bilateral PEX syndrome (group 3) and 27 normal subjects who without PEX syndrome (group 4) were studied. Choroidal thickness were studied in all eyes using a high speed and high resolution Fourier domain-OCT device. OCT features were compared in all groups using the statistical package SPSS v 15.0.
Results
The mean choroidal thickness was measured as 236.25 ± 57.02 µm in group 1, as 327.23 ± 46.84 µm in group 2, as 205,36 ± 73.66µm in group 3 and as 303,15 ± 53.96 µm in group 4. Significant difference in the mean choroidal thickness was found between the group 1 and group 2 (p<0.001), group 1 and group 4 (p=0.004), group 2 and group 3 (p<0.001), group 3 and group 4 (p<0.001). There was no significant difference between group 1 and group 3 (p=0.252) and group 2 and 4 (p=0.491).
Conclusion
In this study, patients with affected PEX syndrome have significantly thinner choroidal thickness as compared to unaffected PEX syndrome.