Hydrogel Ocular Bandages to Protect and Increase Watertight Proprieties of Corneal Incisions After Cataract Surgery: 4-Year Experience

Saturday, April 26, 2014: 1:57 PM
Room 151A (Boston Convention and Exhibition Center)
Gabriele Scaltrini, MD, CMA Centro di Microchirurgia Ambulatoriale, Monza, Italy
Matteo Piovella, MD, CMA Centro Microchirurgia Ambulatoriale, Monza, Italy

Narrative Responses:

Purpose
To evaluate liquid hydrogel ocular bandages (OcuSeal™ and ReSure™) to cover and protect clear corneal cataract surgical incisions.

Methods
At the conclusion of cataract surgery,we applied OcuSeal™liquid bandage(Beaver Visitec International) in 265eyes of198patients(mean age68.61±11.46) or ReSure™Adherent Ocular Bandage(Ocular Therapeutix Massachusetts,USA)in74eyes of65patients(mean age68.11±9.89)to reinforce closure of clear corneal incisions(up to3.75mm).OcuSeal™consists of a synthetic dentritic hydrogel comprised of2separate components:powdered polyethylene glycol(PEG)and liquid polyethylene amine(PEI). Resure™consists of a polyethylene glycol-based hydrogel.Hydrogel is activated by mixing2separate components:powder polyethylene glycol(PEG)and a diluent liquid precursor containing trilysine.After application,both bandages cross-link within30seconds

Results
During the immediate post-operative interval, patients treated with both bandage reported improved comfort.  Resure™  protected the wound by remaining localized over the de-epithelialized tissue for at least 24 hours in 74 eyes (100%) of patients while Ocuseal™  within 12 hours.

Conclusion
Liquid bandage applied at completion of cataract surgery may enhance incisional wound closure and improves post-operative patient comfort. After refilling with BSS, the anterior chamber is increasing with the bandages due to improvement of watertight properties