Stability of Intracapsular Implantation of New Fluid-Filled Injectable Accommodating IOL
Narrative Responses:
Purpose
To confirm results of prior human studies which show that a new accommodating intraocular lens, consisting of a hollow, fluid-filled hydrophobic acrylic optic and oversized, hollow, fluid-filled haptics maintains stable performance when implanted in the capsular bag.
Methods
Thirty patients were enrolled in this prospective, single-arm study of the FluidVision AIOL (PowerVision, Inc., Belmont, CA). Typical IOL study inclusion and exclusion criteria were employed. Performance stability was assessed by comparing measurements taken over time that included cycloplegic refraction, determination by OCT of power calculated from lens thickness and accommodative movement by OCT. Follow-up points which included some or all of these measures were at 3, 6 and 12 months.
Results
At the six-month clinical follow up, spherical equivalent under cycloplegia remained unchanged as compared to the three month follow-up (difference not significant, paired t test, p>0.5). Accommodative movement as well as power determined by lens thickness under cycloplegia remained unchanged between the 3 and 6 month follow-up (p>0.5). This is consistent with prior results in a study of a very similar, non-injectable version of this device, where lens power, as determined by changes in lens thickness, did not show any statistically significant change between 1, 6 and 12 months (p>0.7).
Conclusion
Intracapsular implantation of a fluid-filled AIOL confirms prior studies which show stability of performance out to 1 year.