Amyloidosis of Upper Eyelids
Narrative Responses:
Purpose
To describe a case of upper eyelid amyloidoisis which had been observed more than 8 years
Methods
A 67 year old women was admitted for firm, painless, nodular, slowly growing unilateral lesion of right upper eyelid. She hasn’t been done any ocular examination before. Slitlamp biomicroscopy and fundus examination couldn’t have done completely because of the lesions mass effect. Computed tomography (CT) imaging demonstrated right eyelid swelling and an ill-defined isodense upper eyelid lesion. Magnetic resonance imaging (MRI) was performed for the best soft tissue resolution. The lacrimal gland and orbicularis oris muscle was infiltrated.
Results
The patient underwent partial excision of the tumour-like lesions. Evaluation by light microscopy revealed amorphous supepithelial amophous eosinophilic deposits with Hematoxylin and eosin stained sections and amyloidosis was confirmed by a positive Congo red staining revealing a positive gren birefringes when using with polarized light. An immunohistochemical examination revealed that marked λ -chain-positivity was present in dermis.
Conclusion
General clinical examination and ophthalmologic tests are also indicated to complete preoperative evaluation which should lead to a correct therapeutic strategy, avoiding partial or multiple treatments. A surgical approach alone may often be associated with high risk of incomplete excision and local recurrence, in the early or late postoperative period.