Analysis of Affecting Factors on Macular Thickness Change After Phacoemulsification and IOL Implantation
Narrative Responses:
Purpose
To analyze the cystoid changes of macula and to evaluate the affecting factors on macular thickness after phacoemulsification and IOL implantation.
Methods
A retrospective chart review was performed with the patients who underwent uneventful phacoemulsification and IOL implantation in Seoul National University Hospital, from April 2012 to April 2013 (n=500). The incidence of cystoid macular changes was evaluated. The patients were divided into groups depending on usage of prednisolone or oral NSAIDs, the presence of diabetes mellitus(DM), DM Retinopathy, epiretinal memebrane(ERM), age-related macular degeneration(ARMD), and ocular inflammatory diseases. The changes of macular thickness and edema were measured using optical coherence tomography.
Results
Cystoid macular changes developed in 1.0% of the patients. Administration of oral aceclofenac or oral steroids showed no significant influence in macular thickness change. Patients with ERM or history of uveitis/scleritis showed significant elevation of retinal thicknes (p<0.05, independent t-test). There was no difference in macular thickness change in patients with nonproliferative diabetic retinopathy and proliferative diabetic retinopathy. Presence of ARMD did not have a significant influence in macular thickness change. Logistic regression analysis showed increased probability of 3 standard deviation changes of retinal thickness in patients over 60 years-old(OR 1.946, p=0.014).
Conclusion
This study suggests that the patients with concomitant ocular inflammatory diseases or ERM and aged patients over 60 years may have a risk of macular thickening after phacoemulsification and IOL implantation.