Two Target Locations for Corneal Inlay Implantation Combined With LASIK

Sunday, April 27, 2014: 1:34 PM
Room 154 (Boston Convention and Exhibition Center)
Christine Carole C. Corpuz, MD, Shinagawa LASIK Center, Tokyo, Japan
Satoshi Yukawa, MD, Shinagawa LASIK Center, Tokyo, Japan
Toru Nakamura, MD, Shinagawa LASIK Center, Tokyo, Japan
Tukezban Huseynova, MD, Shinagawa LASIK Center, Tokyo, Japan
Minoru Tomita, MD, PhD, Shinagawa LASIK Center, Chiyoda-ku, Tokyo, Japan

Narrative Responses:

Purpose
To compare the visual acuity outcomes between two target locations for inlay implantation with concurrent LASIK.

Methods
This is a retrospective study of patients who underwent bilateral LASIK with inlay implantation on their non-dominant eye from April 2010 to December 2012.  Two groups were stratified based on the pupil center-to-purkinje distance: small (≤300µm) and large (>300µm).  Each group was divided into subgroups according to the distance of the inlay center to either the purkinje (I-Pk), or the midpoint between the pupil center and purkinje (I-M).  The inlay position was classified 0-100, 101-200, 201-300, or 301-400 microns from both midpoint and purkinje. Uncorrected distance visual acuity (UDVA) and uncorrected near visual acuity (UNVA) were assessed pre and postoperatively.

Results
For the I-M and I-Pk groups comprising 992 patients, both UDVA and UNVA improved (p-value of < 0.0001 for 0-100, 101-200, 201-300, and 301-400μm). Statistical tests showed that there is no significant difference within subgroups of small Pp-Pk distance for I-M (p-value > 0.05 for both UDVA and UNVA), I-Pk (both; p-value > 0.05) and large Pp-Pk distances for I-M (both; p-value > 0.05) and I-Pk (both; p-value > 0.05).  Comparison between subgroups (I-M vs I-Pk) likewise showed no statistical difference (p > 0.05 for 0-100, 101-200, 201-300, and 301-400μm).

Conclusion
Both target locations result in similar and satisfactory visual outcomes.