Two Target Locations for Corneal Inlay Implantation Combined With LASIK
Narrative Responses:
Purpose
To compare the visual acuity outcomes between two target locations for inlay implantation with concurrent LASIK.
Methods
This is a retrospective study of patients who underwent bilateral LASIK with inlay implantation on their non-dominant eye from April 2010 to December 2012. Two groups were stratified based on the pupil center-to-purkinje distance: small (≤300µm) and large (>300µm). Each group was divided into subgroups according to the distance of the inlay center to either the purkinje (I-Pk), or the midpoint between the pupil center and purkinje (I-M). The inlay position was classified 0-100, 101-200, 201-300, or 301-400 microns from both midpoint and purkinje. Uncorrected distance visual acuity (UDVA) and uncorrected near visual acuity (UNVA) were assessed pre and postoperatively.
Results
For the I-M and I-Pk groups comprising 992 patients, both UDVA and UNVA improved (p-value of < 0.0001 for 0-100, 101-200, 201-300, and 301-400μm). Statistical tests showed that there is no significant difference within subgroups of small Pp-Pk distance for I-M (p-value > 0.05 for both UDVA and UNVA), I-Pk (both; p-value > 0.05) and large Pp-Pk distances for I-M (both; p-value > 0.05) and I-Pk (both; p-value > 0.05). Comparison between subgroups (I-M vs I-Pk) likewise showed no statistical difference (p > 0.05 for 0-100, 101-200, 201-300, and 301-400μm).
Conclusion
Both target locations result in similar and satisfactory visual outcomes.