Long-Term Astigmatism Outcomes With UV-Light-Adjustable IOL
Narrative Responses:
Purpose
To assess the long-term astigmatism outcomes achieved with a UV-light adjustable intraocular lens in patients undergoing standard cataract surgery.
Methods
Patients undergoing standard cataract surgery with a 2.75 mm clear corneal incision were implanted with the light adjustable lens (LAL; Calhoun Vision). Adjustment treatments targeted a maximum of 2D spherical and cylindrical correction in myopic, hyperopic, astigmatic, or combination eyes. Adjustment and lock-in (LI) treatments were carried out for 60 to 150 seconds with a 365 nm UV light source. Pupils were dilated to a minimum of 7 mm before UV treatment. Refractive outcomes were followed over 18 months.
Results
122 eyes were analysed in this study. Mean astigmatic cylinder reduced from -0.92±0.66D (range -3.25-0.00D) pre-op to -0.44±0.27D (-0.75-0.00) 3-months post-LI and -0.35D±0.22D (-0.75-0.00) at 18-months post-LI. Spherical equivalent (SE) reduced from 0.34±2.78D pre-op to -0.08±0.17D at final follow-up. 98% of patients had SE within ±0.5D at 18-months. In 21 myopic eyes, cylinder reduced from -1.02±0.63D (-2.50-0.00) pre-op to -0.35±0.18D (-0.750-0.00D) at final-follow-up, and 95% had SE within ±0.5D at 12-months post-LI. In 15 hyperopic eyes, cylinder reduced from -0.98±0.54D (-2.00-0.00D) pre-op to -0.35±0.21D (-0.75-0.00) final follow-up, and 86% had SE within ±0.5D at 12-months post-LI.
Conclusion
The LAL can effectively and safely correct both myopic and hyperopic astigmatism in patients undergoing standard cataract surgery. Correction of upto 2D sphere and cylinder was achieved in this study. The LAL can also correct small deviations from target refraction.