Intracameral Phenylephrine Versus Intracameral Epinephrine as Prophylaxis Against IFIS

Monday, April 28, 2014: 4:11 PM
Room 151A (Boston Convention and Exhibition Center)
Paula Vázquez de Parga, MD, Complexo Hospitalario Universitario Ourense, Ourense, Spain
Ramón Lorente, MD, PhD, Complejo Hospitalario Universitario Ourense, Ourense, Spain
Betty Lorente, MD, Centro de Oftalmología Barraquer, Barcelona, Spain
Victoria de Rojas, MD, PhD, Complexo Hospitalario Universitario A Coruña, Santiago, Spain

Narrative Responses:

Purpose
To evaluate the efficacy of intracameral phenylephrine (IPH) versus intracameral epinephrine administered as prophylaxis against intraoperative floppy iris syndrome (IFIS).

Methods
Prospective, multicenter, randomized, comparative case series of fellow eyes. Twenty patients receiving tamsulosin underwent cataract surgery. One eye of each patient was randomized to receive 0.6 ml of nonpreserved bisulfite-free IPH 1.5% (group 1) or intracameral epinephrine (group 2) at the start of surgery. Routine topical mydriatics were instilled before surgery. Intraoperative iris billowing and prolapse and pupil size were recorded and videotaped. Surgical complications, adverse events, pre- and postoperative pulse rate and blood pressure, and final corrected distance visual acuity, intraocular pressure, and endothelial cell count were recorded.

Main Outcome Measures: Incidence of IFIS and change in pupil size.

Results
Study is on-going. Final results and conclusions will be provided before the deadline January 31, 2014, following guidelines to online submission.

Conclusion
Study is on-going. Final results and conclusions will be provided before the deadline January 31, 2014, following guidelines to online submission.