Cumulative Cystoid Macular Edema Rates After Large Series of MICS IOL Implantations
Narrative Responses:
Purpose
To study the cumulative Cystoid Macular Edema (CME) rate after 4377 implantations during cataract surgery of 4 different hydrophilic acrylic MICS lens.
Methods
This retrospective study comprises all patients who were implanted between 2006 and 2013 with one of the after 4 micro-incision IOLs: MI60 (Bausch and Lomb), CT Asphina (Zeiss), MicroSlim and Micro AY (PhysIOL). The postoperative follow-up ranged from 1 to 84 months. The cumulative incidence rates of Cystoid Macular Edema (CME) were determined by the Kaplan-Meier survival analysis. The Mann-Withney test was performed after 12 months with a significance threshold of 0.05.
Results
The 1-year survival percentage (i.e. the percentage of no CME patients) was 95% for the CT Asphina (95% CI: 95-95); 96% for the MI60 (94% CI: 92-97) ; 100% for the MicroSlim (95% CI: 100-100) and 100% for the Micro AY (95% CI: 100-100). The survival “no CME” curves provide different trends depending on the IOL type according to comorbodity. An UBM exploration was done to analyze the possible correlation between the haptics design and the ciliary muscle irritation, which could be a possible cause of the delayed appearance of CME.
Conclusion
The low occurrence of CME after implantation of micro-incision cataract surgery (MICS) IOLs was confirmed in this study.
We can’t see any contact between ciliary muscle and haptics in case of CME without any comorbidity (MEM Diabetes…).
This study must be continued in the future.