Cumulative Nd:YAG Laser Rates After Large Series of MICS IOL Implantations

Friday, April 25, 2014
KIOSKS (Boston Convention and Exhibition Center)
Gilles Lesieur, MD, Centre IRIDIS, Albi, France

Narrative Responses:

Purpose
To study the cumulative neodymium: YAG (Nd:YAG) laser rate after 4377 implantations during cataract surgery of 4 different hydrophilic acrylic MICS lens.

Methods
This retrospective study comprises all patients who were implanted between 2006 and 2013 with one of the after 4 micro-incision IOLs: AKREOS MICS (Bausch and Lomb), CT Asphina (Zeiss), MicroSlim and Micro AY (PhysIOL). The postoperative follow-up ranges from 1 to 84 months. The cumulative Nd:YAG laser frequency rates in all groups were calculated, and the cumulative incidence rates were defined by Kaplan-Meier survival analysis and Mann-Withney test with a significance threshold of 0.05.

Results
The 1-year survival percentage was 92% for the AKREOS MICS (95% CI :92-92) ; 97% for the CT Asphina (95% CI :97-97) ; 96% for the MicroSlim (95% CI :95-97) ; 96% for the Micro AY (95% CI:95-97) ; the 2-year survival percentage was 59% for the AKREOS MICS (95% CI :49-71) ; 83% for the CT Asphina (95% CI :83-83) ; 87% for the MicroSlim (95% CI :86-88) ; 89% for the Micro AY (95% CI:88-90). Despite the very different aspect of the survival curves, no statistical difference between CT Asphina, MicroSlim and Micro AY was found. The difference was significant between the MicroSlim/Micro AY and AKREOS MICS (p<0.036).

Conclusion
There is no excessive PCO after MICS lens implantation. The cumulative Nd:YAG laser rates after micro-incision implantation were comparable for CT-Asphina, Micro AY and MicroSlim. The AKREOS MICS lens shows the highest PCO rate. This study must be continued in the future.