Effect of Age and Refraction in Presbyopic Patients Implanted With Transparent Shape-Changing Corneal Inlay
Narrative Responses:
Purpose
To analyze the effects of age and preoperative manifest refraction on near and distance visual performance in patients implanted with Raindrop Inlay
Methods
One hundred eighty-eight patients implanted with a corneal inlay in the non-dominant eye were used for this analysis. Age and Manifest refraction (MRSE: -0.50 to +1.50 D) at the time of surgery were used as the preoperative variables. Uncorrected visual acuity (UDVA and UNVA) and task performance without spectacles 3 months after inlay implantation were used as the endpoints to establish visual performance. Patients were followed out to 12M.
Results
Monocular UNVA (p = 0.90) and near task performance (p = 0.97) were not statistically associated with preoperative age or refraction. Average UNVA was better than 20/25 by 3 months postop. In patients with MRSE between +0.25 to +1.50 D, monocular UDVA was also not statistically associated with preoperative age or refraction. In this range, average UDVA was better than 20/25 by 3 months after implantation. Binocularly, nearly all patients have the ability to perform all near and distance visual tasks across the refractive range investigated. At 12M, 95% of corneas were clear and 5% had trace interface inflammation.
Conclusion
Raindrop inlay provides consistent uncorrected vision and task performance that is independent of preoperative age and manifest refraction for patients between +0.25 D and +1.5 D. Good biotolerance was achieved as most inlay eyes remained clear and quiet at the 12M visit.