Normative Data of Retinal Nerve Fiber Layer Thickness Using Spectral-Domain Optical Coherence Tomography in Young Indian Adult Eyes

Monday, April 28, 2014: 1:41 PM
Room 155 (Boston Convention and Exhibition Center)
Vineeth B. Bhimshetty, DNB, M.N. Eye Hospital Pvt Ltd and Dr. M.N Postgraduate Institute Of Ophthalmology, Chennai, India
Murali Ariga, MS DNB, FAICO, Swamy Eye Clinic, chennai, India

Narrative Responses:

Purpose
To study the normative data of retinal nerve fibre layer (RNFL) thickness using Spectral Domain Optical coherence tomography(SD OCT) in young Indian adult eyes

Methods
A hospital based Prospective study,200 healthy young(20-40 years) Indian adult of both sex underwent disc map RNFL analysis using SD OCT in both eyes and 200 eyes were randomly selected.

Inclusion criteria

  1. All subjects with normal ocular examination
  2. IOP < 21 mmHg
  3. BCVA ≥ 20/30,refractive error within ±3 diopters(D)sphere and ± 1.5 D cylinder
  4. Normal appearing optic disc,neuro retinal rim,cup-disc ratio <0.5, no asymmetry in CDR between 2 eyes>0.2 (with +90D stereoscopic lens)

The mean RNFL thickness,4 quadrant average (temporal, superior, nasal, inferior),12 clock-hour averages was generated and the variation of gender and age was determined

Results
Mean ± Standard deviation of  retinal nerve fibre layer thickness  for various quadrants for inferior, superior , nasal and temporal quadrants and mean entire circumference around the optic nerve head were 133.9 ± 25.1, 133.6 ± 21.1, 84.9 ± 20.6, 66.4 ± 16.2 and 105.7 ±  13.2 µm µm respectively. There was statistically significant difference(p value <0.05) in RNFL thickness in age and sex .

Conclusion
Our results provide normal Retinal nerve fibre layer  thickness measurements and its variation with age and sex in normal young Indian adult eyes.These measurements may serve as a reference during glaucoma screening with SD OCT in Indians.