Normative Data of Retinal Nerve Fiber Layer Thickness Using Spectral-Domain Optical Coherence Tomography in Young Indian Adult Eyes
Narrative Responses:
Purpose
To study the normative data of retinal nerve fibre layer (RNFL) thickness using Spectral Domain Optical coherence tomography(SD OCT) in young Indian adult eyes
Methods
A hospital based Prospective study,200 healthy young(20-40 years) Indian adult of both sex underwent disc map RNFL analysis using SD OCT in both eyes and 200 eyes were randomly selected.
Inclusion criteria
- All subjects with normal ocular examination
- IOP < 21 mmHg
- BCVA ≥ 20/30,refractive error within ±3 diopters(D)sphere and ± 1.5 D cylinder
- Normal appearing optic disc,neuro retinal rim,cup-disc ratio <0.5, no asymmetry in CDR between 2 eyes>0.2 (with +90D stereoscopic lens)
The mean RNFL thickness,4 quadrant average (temporal, superior, nasal, inferior),12 clock-hour averages was generated and the variation of gender and age was determined
Results
Mean ± Standard deviation of retinal nerve fibre layer thickness for various quadrants for inferior, superior , nasal and temporal quadrants and mean entire circumference around the optic nerve head were 133.9 ± 25.1, 133.6 ± 21.1, 84.9 ± 20.6, 66.4 ± 16.2 and 105.7 ± 13.2 µm µm respectively. There was statistically significant difference(p value <0.05) in RNFL thickness in age and sex .
Conclusion
Our results provide normal Retinal nerve fibre layer thickness measurements and its variation with age and sex in normal young Indian adult eyes.These measurements may serve as a reference during glaucoma screening with SD OCT in Indians.