Comparison of Femto-LASIK and Small-Incision Lenticule Extraction for Treatment of High Myopia
Narrative Responses:
Purpose
To compare the efficacy, safety, predictability and stability of Femto-LASIK and Small Incision Lenticule Extraction(ReLEx smile) in the treatment of high myopia and myopic astigmatism.
Methods
One eye each of 25 patients was randomly assigned to the Femto-LASIK group and the other eye to the Smail Incision Lenticule Extraction(Smile) group. All eyes had myopia or myopic astigmatism > -7D and < -10 D spherical equivalent. Outcome variables included UDVA, CDVA, Refraction, Wavefront Errors, Tear Film Break Up Time and subjective symptoms. Patients were followed up at the 1 day, 1 week, 1 month, 3 months, 6 months and 1 year post-operative intervals.
Results
UDVA at 1 month for the Femto-LASIK group was 0.96(+/- 0.12) while it was 0.95(+/-0.08) for the Smile group. CDVA for the Femto-LASIK group at 1 month was 0.99 (+/-0.07) for the Femto-LASIK group, while it was 0.97(+/-0.07) for the Smile group. Mean SphEq Refraction at 1 month in the Femto-LASIK group was -0.12D(+/-0.32D) while it was -0.10D(+/-0.25D) for the Smile group. There was a mean change of -0.62D (+/-0.40D) in the refraction between 1 month and 1 year in the Femto-LASIK group while it was -0.31D(+/-0.22D) in the Smile Group (p<0.1). Wavefront and Tear Data are still being analyzed.
Conclusion
Femto-LASIK and Small Incision Lenticule Extraction showed similar efficacy, safety and predictability in the treatment of high myopia. Small Incision Lenticule Extraction has more stable outcomes over 1 year relative to Femto-LASIK.