Effect of Base Curve of Silicone Hydrogel Bandage Contact Lenses on Post-PRK Outcomes

Friday, April 25, 2014
KIOSKS (Boston Convention and Exhibition Center)
Kenneth R. Taylor, BS, Emory University School of Medicine, Atlanta, GA, USA
Vasudha A. Panday, MD, Wilford Hall Ambulatory Surgery Center, San Antonio, TX, USA
Ryan P. Molchan, MD, San Antonio UniformServices Health Education Consortium, Lackland AFB, TX, USA
Matthew Caldwell, MD, Wilford Hall Ambulatory Surgical Center, Lackland AFB, TX, USA
Charles D. Reilly, MD, R,R, F & R Eye Associates, San Antonio, TX, USA

Narrative Responses:

Purpose
To assess the effect on pain, lens loss, and epithelial healing of 8.4mm and 8.8mm base curve senofilcon A silicone hydrogel contact lenses.

Methods
Double masked, randomized, IRB approved prospective study at Lackland AFB. Inclusion criteria: active duty military members deemed to be eligible for PRK, any patients with previous refractive surgery were excluded. Patients randomized to 2 study and 2 control groups. Group 1: OD-8.4mm; OS-8.8mm (n=50), Group 2: OD-8.8mm; OS-8.4mm (n=50), Group 3: two 8.4mm (n=20), Group 4: two 8.8mm (n=20). Outcome measures were pain, time to epithelial closure, lens loss. Pain assessed with pain survey on scale of 1-10 on post-operative day (POD) 1, 4. Day of epithelial closure and any lens loss tracked during standard post-operative visits.

Results
Mean age 30. No contact lens lost in any group. No statistically significant difference in absolute pain on POD 1, 4 in group 1 although trend for 8.8mm base curve to be subjectively more uncomfortable. No significant difference in absolute pain on POD 1, 4 in group 2; no trend for discomfort in either eye. Overall, patients reported more discomfort at POD 4 than POD 1. No significant difference in epithelial closure in any group.

Conclusion
The base curve of senofilcon A contact lenses does not make a significant difference in patient perception of pain. Trend for more discomfort with the 8.8 was noted.  No significant difference in time to epithelial closure.  Either base curve can reliably be used as a bandage lens after PRK.