Trabeculectomy With Collagen Matrix Implant in Patients With Failed Glaucoma Surgery
Narrative Responses:
Purpose
To evaluate the efficacy and outcome of Ologen Collagen Implants in management of patients with failed glaucoma filtering surgery.
Methods
In this prospective interventional case series study, twenty three cases with failed filtering blebs after trabeculectomy underwent trabeculectomy with ologen collagen implant as an adjuvant. The surgical outcome of surgery was evaluated over a follow up period of 6 months. Intraocular pressure (IOP), number of antiglaucoma medications, and complications were evaluated after one week, 1 month, 3months, and 6 months after surgery
Results
The mean age (SD) of patients was 47.78 (19.55). The mean IOP before surgery was 32.26 mmHg (4.7 mmHg). The mean post-operative IOP was significantly reduced after surgery to 20.48 mmHg (3.02 mmHg) after 6 months. The number of antiglaucoma medications was reduced 6 months postoperatively from 3.09 (0.84) to 1.09 (1.16) at 6 months. After 6 months 47.83% of cases achieved complete success of IOP reduction, 39.13% of cases achieved qualified success, and 13.04% of cases failed to reach the defined successful IOP lowering effect.
Conclusion
Trabeculectomy with ologen collagen implant can improve the success of trabeculectomy and significantly reduce IOP in previously operated glaucoma cases.