Comparison of Visual Outcomes After Wavefront-Guided and Wavefront-Optimized LASIK and PRK

Rivers, Bruce

Comparison of Visual Outcomes After Wavefront-Guided and Wavefront-Optimized LASIK and PRK

Friday, April 25, 2014

KIOSKS (Boston Convention and Exhibition Center)

Bruce A. Rivers, MD, Fort Belvoir Army Hospital, Fort Belvoir, VA, USA

Rose Kristine C. Sia, MD, Warfighter Refractive Surgery and Research Center, Fort Belvoir, VA, USA

Denise S. Ryan, MS, Warfighter Refractive Surgery and Research Center, Falls Church, VA, USA

Joseph Pasternak, MD, WR Bethesda, Bethesda, Maryland, USA

Richard Stutzman, MD, Walter Reed National Military Medical Center, Bethesda, Maryland, USA

Kraig S. Bower, MD, Wilmer Eye Institute, Lutherville, MD, USA

Narrative Responses:

Purpose
To compare visual outcomes following wavefront guided (WFG) and wavefront optimized (WFO) LASIK and photorefractive keratectomy (PRK).

Methods
This is a prospective study of 196 myopic patients undergoing either LASIK or PRK, as selected by patient and physician. Participants were randomized to either WFG or WFO treatment. WFG treatments were performed using the VISX CustomVue STAR S4 IR and WFO using the Wavelight Allegretto Wave EyeQ excimer laser systems. Subjective manifest refraction, uncorrected and corrected distance visual acuities (UDVA and CDVA) were determined preoperatively and at 1, 3 and 6 months (M) postoperatively. Loglinear analysis was done to compare 4 surgical techniques.

Results
Mean study population age was 31.0±6.8 years and mean manifest spherical equivalent (MSE) was -3.58±1.57 diopters (D). At 6 months, most eyes achieved UDVA of 20/20 or better (100% WFG LASIK, 99.0% WFG PRK, 98.4%WFO LASIK and 98.0% WFO PRK; p=0.82) and MSE were within 0.50 D of emmetropia (95.0% WFG LASIK, 93.4% WFG PRK, 100.0% WFO LASIK and 95.3% WFO PRK; p=0.19). No one lost 2 or more lines of CDVA in any of the treatment groups at 6 months postoperatively.

Conclusion
Visual outcomes following either LASIK or PRK using either wavefront-guided or optimized technology are excellent and comparable.