Effect of Dry Eye on Higher-Order Aberrations Graded by IR Meibography
To evaluate the effect of diagnosed MGD graded by IR Meibography on HOAs.
Group A, 78 eyes with dry eyes and group B including 33 normal eyes underwent tear film work up including Shirmer 1 test, BUT test, Meibography using tge Sirius corneal analyzer with the phoenix software system for meibography grading and corneal wavefront assessment. Double indexing scheme was used for HOA notation and Strehl ratio was calculated. MGD was graded based on the Arita meiboscore.
Total HOA RMS at 6mm pupil showed higher values in group A 0.565 than group B 0.38 (p 0.001) Coma, Strehl ratio also showed a significant difference between both groups with coma being significantly higher in group A (0.37 vs 0.27) and Strehl ratii being significantly higher in group B (0.16 vs 0.13). A nonsignificant difference between both groups was observed in secondary astigmatism, distribution of coma axis or amount of spherical aberration.
Dry eye has a significant effect on HOAs. Total HOA RMS and coma are affected more than spherical aberration. Meibography is a promising tool and correlates well with other tests for MGD.