Outcome of Same Day Topography-Guided Photorefractive Keratomileusis and Corneal CXL in Patients With Subclinical Keratoconus

Tuesday, April 21, 2015: 8:26 AM
Room 1B (San Diego Convention Center)
Talal A. Althomali, MD

To evaluate the outcome of same day topographic-guided photo-refractive keratomileusis (PRK) and corneal cross-linkage in patients with sub-clinical keratoconus.

One hundred-twenty patients with sub-clinical keratoconus were treated with topographic guided photo-refractive keratectomy and same day corneal collagen cross-linkage with riboflavin and were followed for at least 1 year. Inclusion criteria was low grade myopia of up to 3 diopter spherical equivalent,  corneal thickness more than 475 microns, maximum keratometry reading K max less than 50 D.

Median preoperative spherical equivalent refraction was -2.25 D. At final follow up visit at one year spherical equivalent was statistically significantly reduced to -0.25 D (p<0.001 ). Median preoperative uncorrected visual acuity was 0.25 and best corrected visual acuity was 0.60. Median post-operative uncorrected visual acuity was 0.90 and best corrected visual acuity was 1.0. Median steepest K reading preoperatively was 46.25 D and it was 43.62 D at final follow-up visit.

Same day topographic-guided PRK and corneal cross-linkage is a safe treatment offering good vision in sub-clinical cases of keratoconus.