Retrospective Analysis of an Ocular Sealant for Wound Closure in Post Radial–Keratotomy Cataract Patients

Saturday, April 18, 2015: 1:01 PM
Room 5A (San Diego Convention Center)
Arun C. Gulani, MD

To assess the benefits of the ReSure Sealant in cataract patients who have previously undergone post-radial keratotomy (RK) surgery.

Seven patients (9 eyes) of average age 66 years were examined at a single site following coaxial phacoemulsification clear corneal cataract surgery in patients with previous RK surgery ranging from 8 to 20 cuts.  A median of 2.8 mm biplane incisions were used across the population.  Following Toric lens implantation, the sealant was painted over the incision, and allowed to polymerize for 30 seconds.  Patients were evaluated at 1 day and 1 month for wound healing and adverse events.

At postoperative day 1, IOP presented at a mean 15 mmHg.   Mean UVA for 5 eyes was recorded at 20/60 (2 eyes with Maculopathy excluded).  No fluid egress was noted and all wounds were stable.  At 1 month, mean UVA stabilized at 20/30 with mean spherical equivalent improvement of 73%.  No adverse events were noted and patients were comfortable overall with a comfort survey of 10/10. 

Fragility of the cornea in post-RK patients may lead to excess edema, perforations, hyperopic shifts, or against-the-rule astigmatism.  Although sutures have previously been utilized in these patients to stabilize the wound postoperatively, they can induce additional adverse events.  The sealant proved safe and effective for wound closure in post-RK patients.