Cystoid Macular Edema Rates With Intravitreal Transzonular Antibiotic/Steroid Prophylaxis
Intravitreal transzonular injection of triamcinolone, moxifloxacin with and without vancomycin was assessed for postop cystoid macular edema (CME) incidence after dropless cataract surgery.
Randomized prospective double blind injection of either TriMoxi or TriMoxiVanc was done by two private practice surgeons in different states, and postop Irvine-Gass Syndrome was assessed with OCT in low risk and high risk groups.
Incidence of CME rates in the low risk group were similar and not significant with TriMoxi (1.5%) compared with TriMoxiVanc (1.8%), p<0.05. High risk group CME rates were also similar, modified with variable NSAID use.
Intravitreal vancomycin doesn't increase risk of CME combined with triamcinolone/moxifloxacin with dropless cataract surgery. CME rate is lower than with topical meds.