Multiple Trabecular Micro-Stents as Standalone Procedure in Open-Angle Glaucoma: 1-Year Results

Sunday, April 19, 2015: 1:36 PM
Room 1A (San Diego Convention Center)
Harry Dang, BSc
Arsham Sheybani, MD
Devesh K. Varma, MD, FRCSC
Ike K. Ahmed, MD

To evaluate the intraocular pressure (IOP) lowering effect of multiple trabecular micro-stents as a solo procedure in patients with open-angle glaucoma.

A retrospective review of consecutive eyes that underwent multiple trabecular micro-stents as a solo procedure without cataract extraction by two surgeons in Toronto, Canada was conducted.  Patients were assessed following the procedure on days 1, 7 and months 1, 3, 6, 9, 12 and beyond if applicable. The primary outcome measure was IOP and the secondary outcome measures were the reduction in number of glaucoma medications, corrected distance visual acuity (CDVA), and the number of complications.

A total of 21 eyes of 18 patients were included.  The mean age of the cohort was 63.5 ± 17.6 years.  Mean IOP dropped from 21.4 ± 7.4 mmHg at baseline to 14.4 ± 7.6 mmHg after one day (p=0.02), 18.4 ± 4.4 mmHg after one month (p=0.08), 14.9 ± 4.2 mmHg after three months (p=0.01), and 17.0 ± 5.7 mmHg after 13.3 months (mean) at last follow-up (p=0.03). There was a reduction in mean number of ocular hypotensive medications from baseline to last follow-up postoperatively (3.0 ± 0.7 to 2.2 ± 1.0, p<0.01). There was no significant change in mean CDVA from baseline over the follow-up period.  No vision-threatening complications were observed.

Multiple trabecular micro-stents implanted as a solo procedure resulted in a decrease in IOP and the number of hypotensive medications over 13 months in patients with open-angle glaucoma.