Postoperative Outcomes of Children Operated for Bilateral Ectopia Lentis

Sunday, April 19, 2015: 3:01 PM
Room 1B (San Diego Convention Center)
Rupal H. Trivedi, MD
Jennifer D. Davidson, MD
Dina Tadros, MD
Leah A. Owen, MD, PhD
M. Edward Wilson, MD

To report outcomes of children operated for bilateral ectopia lentis.

Charts of 94 eyes from patients who underwent anterior lensectomy for ectopia lentis by one surgeon were reviewed.  Etiology of Ectopia lentis, pre and postoperative best corrected visual acuity (BCVA), axial length (AL) at surgery and follow up, and complications were reviewed. We excluded unilateral surgery, <3 months of follow-up and age at last follow-up <4 years.

Seventy eyes of 35 patients met inclusion criteria.  19/35 (54.3%) patients had MS.  Age at lensectomy: 6.9 (SD4.4) years; Age at follow-up: 12.2 (SD4.6) years; Follow-up duration: 5.3(SD4.6) years; Preoperative AL: 23.2 (SD1.5). AL growth was 1.3 mm after 4.9 years follow-up.  Although preoperative AL was not statistically significantly between MS and non-MS patients (23.6 vs 22.7 mm, P=0.07), preoperative keratometry was significantly flatter in patients with MS (39.5 vs 41.1 for K1, 41 vs 42.8 for non-MS; P=0.02).  17 eyes received primary IOL implantation, while 53 were left aphakic at the time of lensectomy. 26 of 53 eyes received secondary IOL implantation.  3 eyes had retinal detachment: 2 MS, 1 having Marfan features, (but not confirmed having MS).  10 had glaucoma (2 MS).  The median post-op BCVA was 20/40.

Keratometry values were flatter in patients with MS. Retinal detachment was more common in patients with MS, while glaucoma was more common in patients without MS.