Small-Aperture IOL Visual and Optical Performance Outcomes

Tuesday, April 21, 2015: 8:16 AM
Room 4 (San Diego Convention Center)
Robert Edward T. Ang, MD

Evaluation of visual and optical performance outcomes of patients implanted monocularly with a small aperture hydrophobic acrylic intraocular lens (IC-8 IOL, AcuFocus Inc.).

Ongoing, prospective, non-randomized clinical evaluation.  Twelve patients, presenting for cataract surgery, were implanted monocularly in their non-dominant eye with an IC-8 IOL after uneventful phacoemulsification. The IC-8 IOL is a single-piece intraocular lens with a centrally located opaque annular mask. The mask has a 3.23mm outer diameter, a 1.36mm central aperture and contains 3200 microperforations ranging in size from 7–10 microns. For the fellow eye, 8 patients maintained their natural crystalline lens and 4 patients had a monofocal IOL. ETDRS charts were used to measure uncorrected distance, intermediate and near visual acuities. Additionally, defocus curves were measured at 6 months. Binocular visual acuities are reported in mean letter score ± standard deviation.

Uncorrected binocular visual acuities for distance, intermediate and near are 50.6 ± 3.8 (20/20), 48.5 ± 6.0 (20/20), 45.5 ± 6.4 (20/25) respectively. 20/25 or better uncorrected binocular visual acuities was achieved by 100%, 82% and 91% of patients at distance, intermediate and near respectively. The IC-8 IOL defocus curve follows a similar curve to the KAMRA corneal inlay (AcuFocus, Irvine, CA). IC-8 IOL patients show continuous functional vision of 20/40 or better over a 4.0D range. When paired with a small amount of myopia of -0.75D to -1.00D, the IC-8 IOL improves the visual acuity over a larger range of intermediate and near distances, with minimal effect to distance vision.

Early results demonstrate that monocular implantation of an IC-8 IOL provides excellent visual acuity across all distances.