Clinical Analysis of Inpatient Cases With Culture-Proven Keratitis Over 4 Year Period

Monday, April 20, 2015: 4:12 PM
Room 3 (San Diego Convention Center)
Jinho Jeong, MD, PhD

To investigate the clinical aspects, distribution, prognostic factors of culture-proven inpatients of bacterial and fungal keratitis.

Forty-five positive culture cases from consecutive corneal scrapes of 107 clinically diagnosed keratitis inpatients hospitalized between 2011 and 2014 were retrospectively reviewed. The pathogenic profiles were evaluated.

There were 13 cases of fungal keratitis and 38 cases of bacterial keratitis. 6 cases were isolated with mixed pathogens. Mean age was 63.8 years. The prevalence of DM was 73.3%. Most common cause of keratitis was agriculture (Mandarin orange)-related ocular trauma (44.4%). In the analysis of initial presentation, infiltration size >2mm were observed in 71.1%, and main lesion was central in 42.2%. The resolution of infiltration was observed in 88.9%. Final visual acuity was mostly correlated with initial visual acuity at presentation (p=0.012). Most common fungal isolates was Candida species (5 cases). The most common period of fungal keratitis occurrence was winter (7 cases). Most common bacterial pathogen was Staphylococcus species (12 cases). The occurrence of bacterial keratitis was mainly distributed in spring season (14 cases).

Candida and Staphylococcus species were most common bacterial and fungal keratitis isolates found in Jeju island. Due to the agriculture structure in the Jeju island, the occurrence of fungal keratitis was mostly concentrated in winter season.