Self-Retained Amniotic Membrane for Dendritic Keratitis

Friday, April 17, 2015
KIOSKS (San Diego Convention Center)
Hosam El Sheha, MD, PhD

Purpose
To demonstrate the efficacy of self-retained amniotic membrane after debridement in the treatment of recurrent dendritic keratitis.

Methods
A 70 year-old female, with a history of rheumatoid arthritis and long term systemic steroids, had recurrent episodes of dendritic keratitis despite the frequent use of topical and systemic antivirals. She presented with left ocular pain, photophobia, blurry vision and examination revealed left dendritic corneal ulcer and conjunctival injection.  Corneal debridement was done under topical anesthesia and a self-retained amniotic membrane was placed.

Results
Five days after treatment, ocular pain was decreased, conjunctival inflammation was reduced and corneal epithelialization was complete. The patient continued systemic antiviral for 3 months and the corneal surface remained stable.

Conclusion
Self-retained amniotic membrane after debridement appears effective in treating dendritic keratitis. Early intervention is recommended to remove the infected corneal epithelium, control inflammation, prevent further damage, restore corneal integrity and reduce the potential of scarring.