Clinical Feasibility and Repeatability of Ocular Straylight Measurement in Crosslinked Eyes
Narrative Responses:
Purpose
To evaluate repeatability, accuracy and precision, as well as the clinical feasibility of ocular straylight quantitative measurements in pre- and post-crosslinked eyes as a means to evaluate the possible impact on corneal clarity.
Methods
Scattering in ocular media was quantitatively measured by means of stray light compensation response (C-Quant, Oculus) in 30 healthy eyes (control group A) and in 30 preoperative (group B) and in 30 post-crosslinked (group C) patients (age-matched groups). Repeatability of logarithm of stray light measurements as well as the postoperative change in straylight was assessed.
Results
Repeatability of stray light measurements on healthy eyes was on average ± 0.03 (log s). Repeatability on the preoperative eyes was on average ± 0.045 (log s), and repeatability on the post-operative eyes was ± 0.047 (log s). Mean stray light measurement was 1.02±0.19 log units in the post-operative group compared to the 1.10±0.35 log units in the pre-operative group and 0.94±0.15 in the healthy group. Differences of intraocular straylight log(s) were not statistically significant.
Conclusion
The clinical quantification of post-crosslinking effect in ocular straylight measurement indicates no significant change in ocular scatter.