Comparison of Contrast Sensitivity and Higher-Order Aberrations After Small-Incision Lenticule Extraction and Femtosecond LASIK for Myopia

Friday, April 25, 2014
KIOSKS (Boston Convention and Exhibition Center)
Ahmet Demirok, MD, Beyoglu Eye Training and Research Hospital, Beyoglu, Turkey
Ilker Cankaya, MD, Beyoglu Eye Training and Research Hospital, Istanbul, Turkey
Alper Agca, MD Istanbul, Turkey
Yusuf Yildirim Istanbul, Turkey
Engin B. Ozgurhan, MD, Beyoglu Eye Training and Research Hospital, Istanbul, Turkey
Ercument Bozkurt, Beyoglu Eye Research and Training Hospital, Istanbul, Turkey
Omer F. Yilmaz, MD Istanbul, Turkey

Narrative Responses:

Purpose
To evaluate and compare postoperative contrast sensitivity and higher-order aberrations (HOA) between small-incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK).

Methods
Sixty-four eyes of 32 patients with myopia and astigmatism were enrolled into this prospective comparative case series. Inclusion criteria were spherical equivalent of the subjective manifest refraction (SE) being less than 10 diopters and a difference of less than 0.50 diopters (D) between the SEs of the eyes. One eye of each patient was treated with SMILE and the fellow eye treated with FS-LASIK. Randomisation was performed using a sealed envelope system. Nine-month postoperative outcome measures included the changes in contrast sensitivity and corneal higher-order aberrations. SPSS 20.0 was used for statistical analyses.

Results
The mean age of the patients was 26,52 ± 4,58 years. Fifteen patients (47%) were male and 17 patients (53%) were female. Mesopic and photopic contrast sensitivities of FS-LASIK treated eyes at 1,5 cpd are better than those SMILE group, significantly (p=0,021 and p=0,009). However, there were no significant differences between the groups at 3 cpd, 6 cpd, 12 cpd and 18 cpd. The higher-order aberrations (HOA) after SMILE changed from 0.363 to 0.523 μm, and after FS-LASIK from 0.380 to 0.503 μm. The changes in HOAs were similar between groups (p>0,05).

Conclusion
For the treatment of myopia and astigmatism, SMILE and FS-LASIK techniques are safe and have similar clinical outcomes.