Evaluation of PSF Imaging After Bilateral Implantation of Accommodating or Multifocal IOLs
Narrative Responses:
Purpose
To compare visual quality metrics derived from the Optical Quality Analysis System II (OQAS, Visiometrics), which directly measures the point spread function of the optical system of the eye via a double-pass technique, following bilateral implantation of 3 presbyopia-correcting intraocular lenses (IOLs).
Methods
OQAS evaluation was performed on patients enrolled in a prospective, randomized, partially masked, post-market study of 3 presbyopic- correcting IOLs: Crystalens AO (AT-50-AO, n=52 eyes), ReSTOR +3 (SN6AD1, n=50), and Tecnis Multifocal (ZMA00, n=46). One, 3, and 6 months following bilateral, sequential implantation, point spread (PSF) and modulation transfer (MTF) function parameters, Strehl ratios, and optical scatter index (OSI) were recorded and statistically analyzed for the three groups.
Results
At 6 months, the mean OSI for the Crystalens AO group (1.13) was at least 33% less (p<0.01) than the mean OSI for Tecnis MF (1.83) and ReSTOR (1.98). This correlated with a narrower width at 10% of PSF height for Crystalens AO than ReSTOR (p=0.001) or Tecnis MF (p=0.06). There was no statistical difference in mean OSI between the Tecnis MF and ReSTOR (p=0.57). The mean Strehl ratio was highest for the Tecnis MF group (p<0.04).
Conclusion
The OQAS provides objective measurement of visual quality after presbyopia-correcting IOL implantation, with the Crystalens AO showing the least scatter.