Collamer Copolymer Lens in Anisometropic Amblyopia of Children: 2-Year Follow-up
Purpose
To evaluate the 2-year follow-up results, efficacy, and safety of intraocular Collamer lens implantation (ICL) in anisometropic moderately amblyopic children.
Methods
A non-randomized, non-comparative prospective, interventional study on 12 eyes for 12 children, with myopic anisometropia more than five diopters; non-compliant with glasses or contact lens. Patient's age ranged from four to 14 years, with full assessment of the eye including specular microscopy and anterior segment OCT for all patients, with white to white measurement with Caliper, IOL Master and UBM for un-cooperative children. All had implantation of phakic posterior chamber IOL (ICL) behind the iris under general anesthesia, follow-up for 2 years of BCVA, occlusion therapy and binocularity.
Results
Five boys and seven girls aged 4 to 14 years with a mean UCVA of 0.5 (range between 0.3 -0.7) and mean BCVA 0.7 range (0.4-1.0) (P=.01) with improvement of more than 3 Log Mar lines of BCVA was achieved in all children. Occlusion therapy was done for all children immediately after surgery, follow-up with specular microscopy, anterior segment OCT to evaluate the vaulting and positioning of the ICL.
Conclusion
Phakic posterior chamber ICLs are safe, effective procedure to decrease the difference between both eyes in anisometropic, amblyopic myopic children with good stability in refraction and IOP, predictability, no significant endothelial cell loss after 2 years with better stereopsis and better quality of life.