Impact on Optical Quality of Opacified Versus Clear Monofocal One-Piece IOLs: Laboratory Study
Purpose
Optical bench analysis and comparison of opacified and explanted versus new and clear Oculentis Lentis-LS-502-1 single piece hydrophilic acrylic blue light filtering intraocular lens (IOL).
Methods
In a laboratory study we compared the measurements of modulation transfer function ( MTF ) at 25 lp/mm, 50 lp/mm and 100 lp/mm of opacified and explanted Oculentis Lentis-LS-502-1 single piece hydrophilic acrylic IOLs versus a new and clear one with the same power. For each lens the measurements were repeated 5 times each. Optical bench analyzes were performed with the OptiSpheric IOL (Trioptics, Germany) optical bench.
Results
Mean MTF for the opacified IOLs was 0.859, 0.717 and 0.467 at 25lp/mm, 50lp/mm and 100lp/mm compared to 0.852, 0.701 and 0.434 for the clear models at a 2mm aperture. Mean MTF at a 4mm aperture for the opacified IOLs was 0.682, 0.463 and 0.301 at 25lp/mm, 50lp/mm and 100lp/mm compared to 0.744, 0.578 and 0.410 for the clear models. The was a statistical significant energy loss at 2mm and 4mm apertures comparing opacified to clear IOLs.
Conclusion
MTF was overall better with the clear IOLs compared to the opacified and explanted IOLs. The lower MTF values of the opacified IOLs show an overall deterioration of the optical quality which may be caused by the opacification and enhanced by structural changes in the optic due to manipulations during the explantation.