Posterior Capsule Opacification Development and Glistenings in 2 Hydrophobic Acrylic 1-Piece IOLs: 3-Year Follow-up Intraindividual Comparison

Saturday, April 18, 2015: 1:29 PM
Room 5B (San Diego Convention Center)
Björn Johansson, MD, PhD

To compare 2 hydrophobic intraocular lenses (IOLs) regarding development of posterior capsular opacification (PCO) and glistenings during three years after implantation.

In an intraindividual prospective randomized controlled study 50 patients with bilateral cataract and planned for bilateral cataract surgery participated. Exclusion criteria were known visually disturbing conditions, previous intraocular surgery or any complication damaging lens capsule or zonulae. The first operated eye was randomized to receive either AcrySof IQ IOL or Tecnis One-Piece IOL. The second operated eye received the IOL type not implanted in first eye. Visual acuity and intraocular pressure measurements, slitlamp examination and photography were performed after 1 week, 2 and 3 years. PCO was graded with POCOman software. Glistenings in IOL optic were semiquantitatively measured.

At submission deadline, 2 patients returned for the 3-year follow-up. 6 patients have died. By last date for abstract revision, all remaining 42 patients are expected to have returned for 3-year follow-up. Three of the 50 eyes implanted with a Tecnis IOL have been treated with Nd-YAG-laser capsulotomy because of PCO and visual complaints at submission deadline, all before the 3-year follow-up visit. No AcrySof IQ eye has received Nd-YAG-laser treatment at submission deadline.

At submission deadline 3 eyes with Tecnis IOL and no eye with AcrySof IQ IOL received Nd-YAG-laser treatment. Glistenings developed in most Alcon IOLs, but in only few Tecnis IOLs. Before abstract revision deadline 3-year results on PCO and glistenings for all participants will be submitted, and conclusions updated.